Coronavirus Immune Based Therapies Currently Under Consideration
Learn about the role of immune-based therapies in the treatment of Covid-19. Get information on the different immune-based treatment options available for the illness.
So far, more than 1 million people who had been infected with Covid-19 have recovered. The recoveries can be attributed to the different agents that have been used by doctors to manage the disease. The Food and Drug Administration (FDA), is yet to find an effective and specific cure for Covid-19.
However, through efforts like clinical trials and observational data collected during rapid testing have brought some light. Treatment decisions have majorly been based on the patient’s condition and what a healthcare provider deems best to tackle the disease.
Immune-based therapies have been considered in the treatment of Covid-19. They work by targeting the virus or modulating the immune response.
1. Intravenous Immune Globulin (IVIG)
The treatment guidelines for Covid-19 advises against the use of intravenous immune globulin (IVIG) if it is not specific to the treatment of Covid-19. However, some complications may arise during the therapy of Covid-19 that may require IVIG. In such cases, this immune response modulator can be used. The other recommended uses for intravenous immune globulin (IVIG) is during clinical trials.
2. Interleukin-1 inhibitors and Interleukin-6 inhibitors
This is a group of possible immune-based treatment agents for Covid-19. There have not been many clinical trials done on these. Therefore, there lacks adequate data to recommend the use of the inhibitors or advise against their use. The inhibitors have, however, been used in several instances in managing Covid-19.
3. Janus kinase inhibitors and interferons
The Covid-19 Treatment Guidelines Panel strongly recommends against the use of the two immunomodulators, Janus Kinase, and Interferons. Interferons showed some weaknesses in the treatment of the Middle East respiratory syndrome (MERS). This treatment also lacked efficiency in treating severe respiratory syndrome (SARS), which creates doubt in its ability to manage and treat Covid-19. This Immunomodulator also showed high levels of toxicity.
Janus kinase inhibitors such as baricitinib, on the other hand, have a wide range of immunosuppressive effects, which makes it unsuitable for the treatment of Covid-19.
There are several immune-based therapies for Covid-19 that are being used off-label. There is still a lot of investigation and clinical trials to be done before they are approved. The use of the agents in the treatment of Covid-19 is geared at treating the systemic inflammation that is associated with the disease. Just like many other treatment options, a lot of work needs to be done before immune-based therapies are declared as the specific treatments for Covid-19.
Paul Singh, MHA, BA
Covid Antibody Diagnostics™
A Natures Body Wellness Corporation, Lake Mary FL 32746
Find us on Google under Antibody Diagnostics
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